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kinase 1  (Proteintech)


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    Proteintech kinase 1
    Kinase 1, supplied by Proteintech, used in various techniques. Bioz Stars score: 95/100, based on 48 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/kinase 1/product/Proteintech
    Average 95 stars, based on 48 article reviews
    kinase 1 - by Bioz Stars, 2026-03
    95/100 stars

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    (A) UMAP projection schematics of the cell populations examined by single-cell sequencing ( > 300,000 single-cell profiles) from multiple inflammatory diseases and COVID-19 BALF. (B) Expression levels of the IL32, <t>IRAK1,</t> IFNG, IFNGR1, IFNGR2 genes in sc-RNAseq datasets from multiple inflammatory diseases and COVID-19. (C) Detection of IL-32 protein by ELISA in serum samples from healthy donors and patients with mild and severe COVID-19. Statistical analysis: data shown in (C) are mean values of healthy individuals, HC (n = 16), mild (n = 25) and severe (n = 59) COVID-19 with non-parametric Kruskal-Wallis test with Dunn’s multiple comparisons test vs HC (** p < 0.005, *** p < 0.001).
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    (A) UMAP projection schematics of the cell populations examined by single-cell sequencing ( > 300,000 single-cell profiles) from multiple inflammatory diseases and COVID-19 BALF. (B) Expression levels of the IL32, IRAK1, IFNG, IFNGR1, IFNGR2 genes in sc-RNAseq datasets from multiple inflammatory diseases and COVID-19. (C) Detection of IL-32 protein by ELISA in serum samples from healthy donors and patients with mild and severe COVID-19. Statistical analysis: data shown in (C) are mean values of healthy individuals, HC (n = 16), mild (n = 25) and severe (n = 59) COVID-19 with non-parametric Kruskal-Wallis test with Dunn’s multiple comparisons test vs HC (** p < 0.005, *** p < 0.001).

    Journal: bioRxiv

    Article Title: IL-32 drives inflammatory responses in IFN-γ primed human macrophages via a Myddosome-dependent pathway and is elevated in COVID-19

    doi: 10.1101/2025.05.29.656795

    Figure Lengend Snippet: (A) UMAP projection schematics of the cell populations examined by single-cell sequencing ( > 300,000 single-cell profiles) from multiple inflammatory diseases and COVID-19 BALF. (B) Expression levels of the IL32, IRAK1, IFNG, IFNGR1, IFNGR2 genes in sc-RNAseq datasets from multiple inflammatory diseases and COVID-19. (C) Detection of IL-32 protein by ELISA in serum samples from healthy donors and patients with mild and severe COVID-19. Statistical analysis: data shown in (C) are mean values of healthy individuals, HC (n = 16), mild (n = 25) and severe (n = 59) COVID-19 with non-parametric Kruskal-Wallis test with Dunn’s multiple comparisons test vs HC (** p < 0.005, *** p < 0.001).

    Article Snippet: The coverslips were then transferred to a humid chamber and incubated with primary antibodies for detection of protein components in the Myddosome: MyD88 (Thermo Fisher, PA5-19919), IRAK1 (CST, 4359), IKKγ/NEMO (Thermo Fisher, MA5-32682) and TAK1/MAP3K7 (Thermo Fisher, 700113) in blocking solution for 1 h at RT.

    Techniques: Sequencing, Expressing, Enzyme-linked Immunosorbent Assay